Qualitative and quantitative analysis of complex samples, such as diesel, is a challenging task. Comprehensive two-dimensional gas chromatography (GCxGC) is a powerful tool to analyze organic compounds even in complex matrices. The advantage of GCxGC compared to conventional GC is a vastly-expanded separation space. For this purpose two analytical columns with different separation properties (non-polar and polar) are used in series. The technique is based on continuous collection of the effluent from the primary analytical column and periodic reinjection of small portions of this effluent to a second column. Typically the first one is a non-polar column and compounds are separated depending on their boiling points. The second one is a polar column and separation mechanism based on polarity.